SiteSifter finds highly conserved DNA motifs embedded within coding regions. Each instance of a motif is scored based on the chance that its constituent codons are conserved over and above that required for amino acid conservation.

Find all conserved instances of a motif

Choose a known motif or a custom DNA sequence:

1.   Known motifs: -- select a motif --hsa-miR-1hsa-miR-7hsa-miR-9hsa-let-7ahsa-miR-21hsa-miR-22hsa-miR-24hsa-miR-25hsa-miR-31hsa-miR-95hsa-miR-100hsa-miR-101hsa-miR-103hsa-miR-105hsa-miR-10ahsa-miR-122hsa-miR-124hsa-miR-126hsa-miR-128hsa-miR-132hsa-miR-134hsa-miR-136hsa-miR-137hsa-miR-138hsa-miR-141hsa-miR-143hsa-miR-145hsa-miR-147hsa-miR-149hsa-miR-150hsa-miR-153hsa-miR-154hsa-miR-155hsa-miR-15ahsa-miR-183hsa-miR-184hsa-miR-185hsa-miR-186hsa-miR-187hsa-miR-18ahsa-miR-190hsa-miR-191hsa-miR-192hsa-miR-194hsa-miR-197hsa-miR-198hsa-miR-19ahsa-miR-203hsa-miR-204hsa-miR-205hsa-miR-214hsa-miR-217hsa-miR-218hsa-miR-221hsa-miR-223hsa-miR-224hsa-miR-23ahsa-miR-27ahsa-miR-297hsa-miR-298hsa-miR-29ahsa-miR-300hsa-miR-30ahsa-miR-325hsa-miR-326hsa-miR-328hsa-miR-329hsa-miR-335hsa-miR-33ahsa-miR-340hsa-miR-345hsa-miR-346hsa-miR-34ahsa-miR-34bhsa-miR-365hsa-miR-370hsa-miR-375hsa-miR-377hsa-miR-378hsa-miR-379hsa-miR-380hsa-miR-382hsa-miR-383hsa-miR-384hsa-miR-410hsa-miR-411hsa-miR-412hsa-miR-421hsa-miR-425hsa-miR-431hsa-miR-432hsa-miR-433hsa-miR-451hsa-miR-452hsa-miR-453hsa-miR-484hsa-miR-488hsa-miR-489hsa-miR-492hsa-miR-493hsa-miR-494hsa-miR-495hsa-miR-496hsa-miR-498hsa-miR-500hsa-miR-504hsa-miR-505hsa-miR-510hsa-miR-511hsa-miR-514hsa-miR-521hsa-miR-522hsa-miR-523hsa-miR-539hsa-miR-541hsa-miR-543hsa-miR-544hsa-miR-545hsa-miR-549hsa-miR-550hsa-miR-552hsa-miR-553hsa-miR-554hsa-miR-555hsa-miR-558hsa-miR-561hsa-miR-562hsa-miR-563hsa-miR-564hsa-miR-566hsa-miR-567hsa-miR-568hsa-miR-569hsa-miR-570hsa-miR-572hsa-miR-573hsa-miR-575hsa-miR-577hsa-miR-578hsa-miR-579hsa-miR-581hsa-miR-584hsa-miR-586hsa-miR-587hsa-miR-588hsa-miR-591hsa-miR-592hsa-miR-593hsa-miR-595hsa-miR-596hsa-miR-597hsa-miR-598hsa-miR-599hsa-miR-600hsa-miR-601hsa-miR-602hsa-miR-604hsa-miR-605hsa-miR-606hsa-miR-607hsa-miR-609hsa-miR-610hsa-miR-614hsa-miR-616hsa-miR-617hsa-miR-618hsa-miR-619hsa-miR-621hsa-miR-622hsa-miR-624hsa-miR-625hsa-miR-626hsa-miR-627hsa-miR-629hsa-miR-630hsa-miR-631hsa-miR-633hsa-miR-634hsa-miR-635hsa-miR-636hsa-miR-637hsa-miR-638hsa-miR-639hsa-miR-640hsa-miR-641hsa-miR-642hsa-miR-643hsa-miR-644hsa-miR-645hsa-miR-647hsa-miR-648hsa-miR-650hsa-miR-651hsa-miR-652hsa-miR-653hsa-miR-655hsa-miR-656hsa-miR-657hsa-miR-658hsa-miR-659hsa-miR-660hsa-miR-662hsa-miR-664hsa-miR-665hsa-miR-668hsa-miR-675hsa-miR-720hsa-miR-744hsa-miR-758hsa-miR-760hsa-miR-765hsa-miR-766hsa-miR-802hsa-miR-873hsa-miR-874hsa-miR-877hsa-miR-887hsa-miR-888hsa-miR-889hsa-miR-890hsa-miR-920hsa-miR-921hsa-miR-923hsa-miR-924hsa-miR-933hsa-miR-934hsa-miR-935hsa-miR-937hsa-miR-938hsa-miR-939hsa-miR-940hsa-miR-941hsa-miR-942hsa-miR-943hsa-miR-944hsa-miR-106ahsa-miR-1178hsa-miR-1179hsa-miR-1180hsa-miR-1181hsa-miR-1182hsa-miR-1183hsa-miR-1184hsa-miR-1185hsa-miR-1197hsa-miR-1200hsa-miR-1201hsa-miR-1202hsa-miR-1203hsa-miR-1204hsa-miR-1206hsa-miR-1208hsa-miR-1226hsa-miR-1227hsa-miR-1228hsa-miR-1229hsa-miR-1231hsa-miR-1234hsa-miR-1236hsa-miR-1237hsa-miR-1238hsa-miR-1243hsa-miR-1244hsa-miR-1245hsa-miR-1246hsa-miR-1247hsa-miR-1249hsa-miR-1250hsa-miR-1251hsa-miR-1252hsa-miR-1253hsa-miR-1254hsa-miR-1256hsa-miR-1257hsa-miR-1258hsa-miR-1259hsa-miR-1260hsa-miR-1261hsa-miR-1262hsa-miR-1263hsa-miR-1264hsa-miR-1265hsa-miR-1266hsa-miR-1267hsa-miR-1268hsa-miR-1269hsa-miR-1270hsa-miR-1271hsa-miR-1272hsa-miR-1273hsa-miR-1275hsa-miR-1276hsa-miR-1277hsa-miR-1278hsa-miR-1279hsa-miR-1281hsa-miR-1282hsa-miR-1283hsa-miR-1284hsa-miR-1285hsa-miR-1286hsa-miR-1287hsa-miR-1288hsa-miR-1289hsa-miR-1290hsa-miR-1291hsa-miR-1292hsa-miR-1293hsa-miR-1294hsa-miR-1295hsa-miR-1296hsa-miR-1297hsa-miR-1298hsa-miR-1299hsa-miR-1300hsa-miR-1301hsa-miR-1302hsa-miR-1303hsa-miR-1304hsa-miR-1305hsa-miR-1306hsa-miR-1307hsa-miR-1308hsa-miR-130ahsa-miR-1321hsa-miR-1323hsa-miR-1324hsa-miR-133ahsa-miR-135ahsa-miR-1468hsa-miR-1469hsa-miR-146ahsa-miR-1470hsa-miR-1471hsa-miR-147bhsa-miR-148ahsa-miR-1537hsa-miR-1538hsa-miR-1539hsa-miR-181ahsa-miR-1825hsa-miR-1826hsa-miR-1827hsa-miR-1908hsa-miR-1909hsa-miR-1910hsa-miR-1911hsa-miR-1912hsa-miR-1913hsa-miR-1914hsa-miR-1915hsa-miR-196ahsa-miR-200bhsa-miR-208ahsa-miR-216ahsa-miR-220bhsa-miR-220chsa-miR-302ahsa-miR-302fhsa-miR-320ahsa-miR-374ahsa-miR-376ahsa-miR-376chsa-miR-450ahsa-miR-487ahsa-miR-487bhsa-miR-513bhsa-miR-513chsa-miR-517ahsa-miR-517bhsa-miR-518ehsa-miR-520ghsa-miR-526bhsa-miR-548ghsa-miR-548mhsa-miR-548nhsa-miR-548phsa-miR-551ahsa-miR-663bhsa-miR-891ahsa-miR-891bhsa-miR-892ahsa-miR-1255ahsa-miR-1274ahsa-miR-1274bhsa-miR-28-3phsa-miR-28-5phsa-miR-103-ashsa-miR-127-3phsa-miR-127-5phsa-miR-129-3phsa-miR-129-5phsa-miR-139-3phsa-miR-139-5phsa-miR-140-3phsa-miR-140-5phsa-miR-142-3phsa-miR-142-5phsa-miR-151-3phsa-miR-151-5phsa-miR-188-5phsa-miR-219-5phsa-miR-296-3phsa-miR-296-5phsa-miR-299-3phsa-miR-299-5phsa-miR-323-3phsa-miR-323-5phsa-miR-324-5phsa-miR-330-3phsa-miR-331-3phsa-miR-331-5phsa-miR-337-3phsa-miR-337-5phsa-miR-338-3phsa-miR-338-5phsa-miR-339-3phsa-miR-342-3phsa-miR-342-5phsa-miR-34c-3phsa-miR-361-3phsa-miR-361-5phsa-miR-362-5phsa-miR-369-3phsa-miR-369-5phsa-miR-371-3phsa-miR-371-5phsa-miR-409-3phsa-miR-409-5phsa-miR-423-3phsa-miR-423-5phsa-miR-455-5phsa-miR-483-3phsa-miR-483-5phsa-miR-485-3phsa-miR-485-5phsa-miR-486-3phsa-miR-486-5phsa-miR-490-3phsa-miR-490-5phsa-miR-491-3phsa-miR-491-5phsa-miR-499-3phsa-miR-501-3phsa-miR-502-5phsa-miR-508-5phsa-miR-509-3phsa-miR-512-3phsa-miR-515-5phsa-miR-524-3phsa-miR-532-5phsa-miR-542-3phsa-miR-542-5phsa-miR-556-3phsa-miR-556-5phsa-miR-574-3phsa-miR-574-5phsa-miR-576-3phsa-miR-576-5phsa-miR-582-3phsa-miR-582-5phsa-miR-590-3phsa-miR-615-3phsa-miR-615-5phsa-miR-628-5phsa-miR-654-3phsa-miR-671-3phsa-miR-671-5phsa-miR-767-3phsa-miR-767-5phsa-miR-769-5phsa-miR-770-5phsa-miR-875-3phsa-miR-875-5phsa-miR-885-3phsa-miR-885-5phsa-miR-886-3phsa-miR-886-5phsa-miR-1207-3phsa-miR-1207-5phsa-miR-1224-3phsa-miR-1224-5phsa-miR-1225-3phsa-miR-1225-5phsa-miR-125a-3phsa-miR-125a-5phsa-miR-146b-3phsa-miR-193a-3phsa-miR-193a-5phsa-miR-199a-3phsa-miR-450b-3phsa-miR-450b-5phsa-miR-513a-3phsa-miR-516a-3phsa-miR-516a-5phsa-miR-518a-3phsa-miR-518a-5phsa-miR-518d-5phsa-miR-520a-5phsa-miR-520d-5phsa-miR-548a-3phsa-miR-548a-5phsa-miR-548b-3phsa-miR-548c-3phsa-miR-548d-3phsa-miR-219-1-3phsa-miR-219-2-3phsa-miR-1hsa-miR-7hsa-miR-9hsa-let-7ahsa-let-7dhsa-miR-17hsa-miR-21hsa-miR-22hsa-miR-24hsa-miR-25hsa-miR-31hsa-miR-32hsa-miR-95hsa-miR-96hsa-miR-100hsa-miR-101hsa-miR-103hsa-miR-105hsa-miR-10ahsa-miR-122hsa-miR-124hsa-miR-126hsa-miR-128hsa-miR-132hsa-miR-134hsa-miR-136hsa-miR-137hsa-miR-138hsa-miR-141hsa-miR-143hsa-miR-144hsa-miR-145hsa-miR-147hsa-miR-149hsa-miR-150hsa-miR-153hsa-miR-154hsa-miR-155hsa-miR-15ahsa-miR-182hsa-miR-183hsa-miR-184hsa-miR-185hsa-miR-186hsa-miR-187hsa-miR-18ahsa-miR-190hsa-miR-191hsa-miR-192hsa-miR-194hsa-miR-197hsa-miR-198hsa-miR-19ahsa-miR-202hsa-miR-203hsa-miR-204hsa-miR-205hsa-miR-210hsa-miR-214hsa-miR-215hsa-miR-217hsa-miR-218hsa-miR-221hsa-miR-223hsa-miR-224hsa-miR-23ahsa-miR-27ahsa-miR-297hsa-miR-298hsa-miR-29ahsa-miR-300hsa-miR-30ahsa-miR-325hsa-miR-326hsa-miR-328hsa-miR-329hsa-miR-335hsa-miR-33ahsa-miR-340hsa-miR-345hsa-miR-346hsa-miR-34ahsa-miR-34bhsa-miR-363hsa-miR-365hsa-miR-370hsa-miR-372hsa-miR-373hsa-miR-375hsa-miR-377hsa-miR-378hsa-miR-379hsa-miR-380hsa-miR-382hsa-miR-383hsa-miR-384hsa-miR-410hsa-miR-411hsa-miR-412hsa-miR-421hsa-miR-424hsa-miR-425hsa-miR-431hsa-miR-432hsa-miR-433hsa-miR-448hsa-miR-451hsa-miR-452hsa-miR-453hsa-miR-454hsa-miR-484hsa-miR-488hsa-miR-489hsa-miR-492hsa-miR-493hsa-miR-494hsa-miR-495hsa-miR-496hsa-miR-498hsa-miR-500hsa-miR-503hsa-miR-504hsa-miR-505hsa-miR-507hsa-miR-510hsa-miR-511hsa-miR-514hsa-miR-521hsa-miR-522hsa-miR-523hsa-miR-539hsa-miR-541hsa-miR-543hsa-miR-544hsa-miR-545hsa-miR-549hsa-miR-550hsa-miR-552hsa-miR-553hsa-miR-554hsa-miR-555hsa-miR-557hsa-miR-558hsa-miR-559hsa-miR-561hsa-miR-562hsa-miR-563hsa-miR-564hsa-miR-566hsa-miR-567hsa-miR-568hsa-miR-569hsa-miR-570hsa-miR-571hsa-miR-572hsa-miR-573hsa-miR-575hsa-miR-577hsa-miR-578hsa-miR-579hsa-miR-580hsa-miR-581hsa-miR-583hsa-miR-584hsa-miR-585hsa-miR-586hsa-miR-587hsa-miR-588hsa-miR-589hsa-miR-591hsa-miR-592hsa-miR-593hsa-miR-595hsa-miR-596hsa-miR-597hsa-miR-598hsa-miR-599hsa-miR-600hsa-miR-601hsa-miR-602hsa-miR-603hsa-miR-604hsa-miR-605hsa-miR-606hsa-miR-607hsa-miR-608hsa-miR-609hsa-miR-610hsa-miR-611hsa-miR-612hsa-miR-613hsa-miR-614hsa-miR-616hsa-miR-617hsa-miR-618hsa-miR-619hsa-miR-620hsa-miR-621hsa-miR-622hsa-miR-623hsa-miR-624hsa-miR-625hsa-miR-626hsa-miR-627hsa-miR-629hsa-miR-630hsa-miR-631hsa-miR-632hsa-miR-633hsa-miR-634hsa-miR-635hsa-miR-636hsa-miR-637hsa-miR-638hsa-miR-639hsa-miR-640hsa-miR-641hsa-miR-642hsa-miR-643hsa-miR-644hsa-miR-645hsa-miR-646hsa-miR-647hsa-miR-648hsa-miR-649hsa-miR-650hsa-miR-651hsa-miR-652hsa-miR-653hsa-miR-655hsa-miR-656hsa-miR-657hsa-miR-658hsa-miR-659hsa-miR-660hsa-miR-661hsa-miR-662hsa-miR-663hsa-miR-664hsa-miR-665hsa-miR-668hsa-miR-675hsa-miR-720hsa-miR-744hsa-miR-758hsa-miR-760hsa-miR-765hsa-miR-766hsa-miR-802hsa-miR-873hsa-miR-874hsa-miR-877hsa-miR-887hsa-miR-888hsa-miR-889hsa-miR-890hsa-miR-920hsa-miR-921hsa-miR-922hsa-miR-923hsa-miR-924hsa-miR-933hsa-miR-934hsa-miR-935hsa-miR-936hsa-miR-937hsa-miR-938hsa-miR-939hsa-miR-940hsa-miR-941hsa-miR-942hsa-miR-943hsa-miR-944hsa-miR-99bhsa-miR-106ahsa-miR-106bhsa-miR-1178hsa-miR-1179hsa-miR-1180hsa-miR-1181hsa-miR-1182hsa-miR-1183hsa-miR-1184hsa-miR-1185hsa-miR-1197hsa-miR-1200hsa-miR-1201hsa-miR-1202hsa-miR-1203hsa-miR-1204hsa-miR-1205hsa-miR-1206hsa-miR-1208hsa-miR-1226hsa-miR-1227hsa-miR-1228hsa-miR-1229hsa-miR-1231hsa-miR-1233hsa-miR-1234hsa-miR-1236hsa-miR-1237hsa-miR-1238hsa-miR-1243hsa-miR-1244hsa-miR-1245hsa-miR-1246hsa-miR-1247hsa-miR-1248hsa-miR-1249hsa-miR-1250hsa-miR-1251hsa-miR-1252hsa-miR-1253hsa-miR-1254hsa-miR-1256hsa-miR-1257hsa-miR-1258hsa-miR-1259hsa-miR-1260hsa-miR-1261hsa-miR-1262hsa-miR-1263hsa-miR-1264hsa-miR-1265hsa-miR-1266hsa-miR-1267hsa-miR-1268hsa-miR-1269hsa-miR-1270hsa-miR-1271hsa-miR-1272hsa-miR-1273hsa-miR-1275hsa-miR-1276hsa-miR-1277hsa-miR-1278hsa-miR-1279hsa-miR-1280hsa-miR-1281hsa-miR-1282hsa-miR-1283hsa-miR-1284hsa-miR-1285hsa-miR-1286hsa-miR-1287hsa-miR-1288hsa-miR-1289hsa-miR-1290hsa-miR-1291hsa-miR-1292hsa-miR-1293hsa-miR-1294hsa-miR-1295hsa-miR-1296hsa-miR-1297hsa-miR-1298hsa-miR-1299hsa-miR-1300hsa-miR-1301hsa-miR-1302hsa-miR-1303hsa-miR-1304hsa-miR-1305hsa-miR-1306hsa-miR-1307hsa-miR-1308hsa-miR-130ahsa-miR-1321hsa-miR-1322hsa-miR-1323hsa-miR-1324hsa-miR-133ahsa-miR-135ahsa-miR-1468hsa-miR-1469hsa-miR-146ahsa-miR-1470hsa-miR-1471hsa-miR-147bhsa-miR-148ahsa-miR-1537hsa-miR-1538hsa-miR-1539hsa-miR-181ahsa-miR-1825hsa-miR-1826hsa-miR-1827hsa-miR-1908hsa-miR-1909hsa-miR-1910hsa-miR-1911hsa-miR-1912hsa-miR-1913hsa-miR-1914hsa-miR-1915hsa-miR-196ahsa-miR-200bhsa-miR-208ahsa-miR-216ahsa-miR-216bhsa-miR-220ahsa-miR-220bhsa-miR-220chsa-miR-302ahsa-miR-302fhsa-miR-320ahsa-miR-374ahsa-miR-374bhsa-miR-376ahsa-miR-376chsa-miR-450ahsa-miR-487ahsa-miR-487bhsa-miR-513bhsa-miR-513chsa-miR-516bhsa-miR-517ahsa-miR-517bhsa-miR-518bhsa-miR-518ehsa-miR-519ahsa-miR-519ehsa-miR-520fhsa-miR-520ghsa-miR-526bhsa-miR-548ehsa-miR-548ghsa-miR-548khsa-miR-548lhsa-miR-548mhsa-miR-548nhsa-miR-548ohsa-miR-548phsa-miR-551ahsa-miR-663bhsa-miR-675bhsa-miR-891ahsa-miR-891bhsa-miR-892ahsa-miR-892bhsa-miR-1255ahsa-miR-1255bhsa-miR-1274ahsa-miR-1274bhsa-miR-28-3phsa-miR-28-5phsa-miR-103-ashsa-miR-127-3phsa-miR-127-5phsa-miR-129-3phsa-miR-129-5phsa-miR-139-3phsa-miR-139-5phsa-miR-140-3phsa-miR-140-5phsa-miR-142-3phsa-miR-142-5phsa-miR-151-3phsa-miR-151-5phsa-miR-188-3phsa-miR-188-5phsa-miR-219-5phsa-miR-296-3phsa-miR-296-5phsa-miR-299-3phsa-miR-299-5phsa-miR-323-3phsa-miR-323-5phsa-miR-324-3phsa-miR-324-5phsa-miR-330-3phsa-miR-330-5phsa-miR-331-3phsa-miR-331-5phsa-miR-337-3phsa-miR-337-5phsa-miR-338-3phsa-miR-338-5phsa-miR-339-3phsa-miR-339-5phsa-miR-342-3phsa-miR-342-5phsa-miR-34c-3phsa-miR-34c-5phsa-miR-361-3phsa-miR-361-5phsa-miR-362-5phsa-miR-369-3phsa-miR-369-5phsa-miR-371-3phsa-miR-371-5phsa-miR-409-3phsa-miR-409-5phsa-miR-423-3phsa-miR-423-5phsa-miR-455-3phsa-miR-455-5phsa-miR-483-3phsa-miR-483-5phsa-miR-485-3phsa-miR-485-5phsa-miR-486-3phsa-miR-486-5phsa-miR-490-3phsa-miR-490-5phsa-miR-491-3phsa-miR-491-5phsa-miR-499-3phsa-miR-499-5phsa-miR-501-3phsa-miR-501-5phsa-miR-502-5phsa-miR-508-3phsa-miR-508-5phsa-miR-509-3phsa-miR-512-3phsa-miR-512-5phsa-miR-515-3phsa-miR-515-5phsa-miR-524-3phsa-miR-532-3phsa-miR-532-5phsa-miR-542-3phsa-miR-542-5phsa-miR-556-3phsa-miR-556-5phsa-miR-574-3phsa-miR-574-5phsa-miR-576-3phsa-miR-576-5phsa-miR-582-3phsa-miR-582-5phsa-miR-590-3phsa-miR-590-5phsa-miR-615-3phsa-miR-615-5phsa-miR-628-3phsa-miR-628-5phsa-miR-654-3phsa-miR-671-3phsa-miR-671-5phsa-miR-767-3phsa-miR-767-5phsa-miR-769-3phsa-miR-769-5phsa-miR-770-5phsa-miR-875-3phsa-miR-875-5phsa-miR-876-3phsa-miR-876-5phsa-miR-885-3phsa-miR-885-5phsa-miR-886-3phsa-miR-886-5phsa-miR-1207-3phsa-miR-1207-5phsa-miR-1224-3phsa-miR-1224-5phsa-miR-1225-3phsa-miR-1225-5phsa-miR-125a-3phsa-miR-125a-5phsa-miR-146b-3phsa-miR-193a-3phsa-miR-193a-5phsa-miR-199a-3phsa-miR-199a-5phsa-miR-450b-3phsa-miR-450b-5phsa-miR-513a-3phsa-miR-513a-5phsa-miR-516a-3phsa-miR-516a-5phsa-miR-518a-3phsa-miR-518a-5phsa-miR-518d-5phsa-miR-520a-5phsa-miR-520d-5phsa-miR-548a-3phsa-miR-548a-5phsa-miR-548b-3phsa-miR-548c-3phsa-miR-548d-3phsa-miR-219-1-3phsa-miR-219-2-3phsa-miR-509-3-5p

Or

2.   Enter a custom motif: (length 6-8)

with conservation in at least 17 16 15 14 genomes (scoring only available for 17-genome conservation).

Find all conserved motifs contained in a given gene

Enter a gene symbol:     

with conservation in at least 17 16 15 14 genomes (scoring only available for 17-genome conservation).

References